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Of 297 patients with metastatic testicular and extragonadal germ cell tumours (GCT), bone involvement was detected clinically in 3% (7/251) of those at first presentation and in 9% (4/46) of relapsed cases.
The average time from when bone involvement was detected until the patient died was 15.9 months (± 13.2, CI 6.7 25.1), and the average lifespan of patients with bone metastasis after initial diagnosis of colorectal cancer was 42.4 months (± 18.1, CI 29.8 54.9).
Similar(58)
Simultaneous bone marrow and lymph node involvement was detected in 5 of 104 patients, in 1 case by micrometastasis.
Osseous involvement was detected on radiographs as subtle bone erosion of the distal femur anterior cortex.
No intracranial involvement was detected in the current study.
Lymph node involvement was detected in two (3.9%) patients.
Central nervous system involvement was detected in 6 patients.
Hence bone involvement was not present in our population.
Furthermore, the IPS of all patients with bone involvement was higher.
Bone involvement is usually present in patients, and the imaging findings are pathognomonic of ECD.
Bone involvement is bilateral and symmetric with diaphyseal and metaphyseal heterogeneous osteosclerosis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com