"We [had] hypothesised that increased calcium intake would result in better adolescent bone gain," said one researcher.
Bone loss and bone gain were computer simulated in 17 regions of interest on baseline radiographs.
Within both, young and adult mice, Sost KO mice had a greater load-induced total bone gain (Ct.Ar/T.Ar, Ct.Th) than LC mice (Fig. 2, Table 1).
Intermittent administration of parathyroid hormone (PTH) induces bone remodeling and renewed bone modeling, resulting in net bone gain.
Another study tracked 81 adolescents for six years and found that those who had the highest daily caffeine intake had no difference in bone gain or bone density at the end of the study than those with the lowest.
It has been postulated that physical activity may not lead to any additional bone gain during sclerostin inhibition, since the down-regulation of sclerostin was thought to be a mandatory step in the anabolic response to loading6.
In Caucasians, net bone loss was greater in women than men because periosteal bone gain was less in women (40%) than men (56%), endosteal bone loss was similar.
Adequate protein intake during development is critical to ensure optimal bone gain and to attain a higher peak bone mass later on.
Results: Because of exhausted developer, bone loss was relatively underestimated from 6.6%too 16.5% (P <.05), whereas bone gain was relatively overestimated from 9.7%too 16.7% (P <.05).
The average bone gain in studies that used conventional surgical instruments was 3.61 mm, while this was 3.69 mm in those that used ultrasound.
Because the time course of bone loss or bone gain distribution was not uniform in the metaphyses of the tibia, we subdivided the PTM into three zones (medial, central, and lateral) to observe the different bone loss or bone gain patterns after ovariectomy and/or raised cages.
