Bone fractures, malformations, surgical removal of tumors and periodontitis can cause bone defects that interfere with normal bone function and configuration and have become serious clinical problems.
Mechanical forces are essential for normal adult bone function and repair, but the impact of prenatal muscle contractions on bone development remains to be explored in depth in mammalian model systems.
Other criteria included Eastern Cooperative Oncology Group performance status of 0, 1, or 2; adequate renal, hepatic, and bone marrow function; and normal left ventricular ejection fraction assessed by echocardiogram or multigated acquisition scan.
The patients had advanced solid tumours refractory to standard therapy, World Health Organization performance status of 0, 1 or 2, an estimated life expectancy of at least 3 months, adequate bone marrow function, and normal liver and renal function.
The inclusion criteria were (1) a histological or cytological diagnosis of advanced CRC; (2) hospitalization between February 1 , 2012 and August 30, 2012; (3) an unresectable tumor at the first diagnosis and relapsed or metastatic CRC after surgery; (4) adequate kidney, bone marrow, and liver function and normal coagulation.
Vitamin A is well known to be important for animal growth, development and various physiological processes, such as keeping the normal sight and bone function, especially in neonatal and growing animals [ 1].
This investigation in adult patients with severe, chronic post-traumatic or post-operative bone infections and normal renal function demonstrated that these novel calcium sulfate-based bone void filler beads with gentamicin are a clinically useful local antibiotic delivery system and bone void filler/ bone substitute which can be used as an alternative to other anti-infective implants.
Therefore, honey may be able to be recommended to female athletes for maintaining their bone health and normal reproductive functions.
Connexins are vital for normal heart and bone function (Radosinska et al., 2011; Saura et al., 2010; Zhang et al., 2006), and can regulate ROS transfer (Taniguchi Ishikawa et al., 2012).
Most of these patients had a favorable PS, no bulky mass, no evidence of B symptoms, no liver, spleen, or bone marrow involvement, and normal liver function.
