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In contrast, in AS, local peri-inflammatory bone formation is increased, resulting in healing of erosions, ossifying enthesitis, and potential ankylosis of sacroiliac joints and of intervertebral connections.
In contrast, peri-inflammatory bone formation is increased in AS, resulting in healing of erosions, ossifying enthesitis, and potential ankylosis of sacroiliac joints and intervertebral connections, and this changes the biomechanical competence of the spine.
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When rhBMP-2 was used to repair bone defects that remain after cyst enucleation, new bone formation was increased.
Bone formation was increased in a time-dependent manner and could be detected through the 3D images.
Dynamic histomorphometry indicated that bone formation was increased by PTH at both cortical and trabecular surfaces, whereas PRO increased osteoblast number and surface on trabecular surfaces.
At three weeks, the amount of bone formation was increased till about 10% for the titanium group and 18% for the ceramic group.
Quantification of the Ca-P cement implants showed that bone formation was increased significantly by administration of rhBMP-2 (10 weeks pore fill: 53.0±5.4%), and also reached a reasonable amount without rhBMP-2 (43.1±10.4%).
In addition, bone formation was increased in the TM injected CatnbEx3/+; Col2a1-CreER embryos indicated by von Kossa staining (Fig. 4A), suggesting that Wnt/ β-catenin signaling in chondrocytes may also promote bone formation in the perichondrium non-cell autonomously.
21 Bone formation was increased and bone resorption was decreased in the AnTT-treated group in that study, 21 whereas only bone formation was increased in the present study.
In addition, markers of bone resorption and cartilage destruction were increased in arthritic mice, whereas markers of bone formation were increased in ovariectomized mice.
Bone formation was increased between days 3 and 9, peaking at 0.34 ± 0.06 mm/day, and resorption stayed constant at 0.11 ± 0.03 mm/day.
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