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Bone formation could be divided into 2 patterns: one was lamellar bone formation based on the pre-existing trabeculae, and the other was woven bone formation like islands in appearance to connect the 2 sides of the fracture.
In this study, we developed an effective approach to in vivo bone formation based on the process of intermembranous ossification.
If we associate the external mechanical loading parameters with bone remodeling, then we will most likely be able to predict the periosteal new bone formation based on the strain gradient [ 9, 35, 36].
Tarkka et al. confirmed that VEGF promotes bone healing by accelerating endochondral bone formation based on adenoviral-VEGF gene transfer by injecting adenoviral VEGF-A into the muscle layer surrounding the bone defect [ 86].
In this study we investigated the effects of Bis, alone or in combination with statins, on bone resorption and bone formation based on BMD and various bone markers in patients with RA who had been receiving Bis for more than 4 years.
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RA is typically characterized by bone erosion, whereas the main structural out come in AS is bony spur formation based on bone formation.
b Cluster formation based on CHEV value.
These findings demonstrated that limonin has beneficial bone metabolism effects based on bone formation and might have potential as a functional food ingredients and a dietary supplement for osteoporosis.
Bone formation was evaluated based on μCT analysis, histomorphometric analysis and fluorescence analysis.
Eptotermin alfa, also called human bone morphogenetic protein-7 (BMP-7), was originally isolated from bone based on its ability to induce new bone formation in vivo when combined with an appropriate physical support for matrix cellular attachment.
For instance, 160 million cells would be required for 20 cubic centimeter of tissue engineered bone implant based on using 8 million cells/cm scaffold [ 15, 16] to gain substantial bone formation.
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