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Methodological difficulties in nasal bone examination in the first trimester have been reported in the FASTER trial by Malone et al., in which well-trained sonographers who had little previous experience in evaluation of the nasal bone were able to depict the nasal bone in only 75.9% of 6316 fetuses [ 18].
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Difficulties in nasal bone examination experienced by our examiners were similar to those in nuchal translucency measurement, but nuchal translucency could be measured in either the prone or supine position of the fetus.
MRI showed better sensitivity than immuno-PET/CT for bone examination, but immuno-PET/CT allowed detection of bone lesions in areas not explored by MRI (Fig. 23).
Bone marrow examination in terms of cellular morphology was done by Wright staining with bone marrow smear.
It stems from two possible reasons: i) in general, bone marrow is seldom the sole site of systemic involvement by malignant disease and ii) bone marrow examination in evaluating patients with suspected malignancy has a limited value unless supported by some other clinical finding, such as a leukoerythroblastic reaction [ 1, 3, 4].
The diagnostic workup involved bone marrow examination in 300 (91.7%) and skeletal survey in 223 (68.2%) patients.
Table 2 provides the molecular classification of MM based on cytogenetic studies performed on bone marrow examination in this cohort.
Bone marrow examination yielded positive results in the majority of patients with miliary TB when it was carried out [ 16], although the place of bone marrow examination in the absence of haematological abnormalities requires clarification.
A national study of the performance of bone marrow examination in newly diagnosed Hodgkin's disease was undertaken to establish current practice.
However, whether a more precise assessment of CR including bone marrow examination in addition to serologic testing is necessary has not yet been evaluated.
Neither a distinct tumor mass nor apparent lymph node enlargement was noted in six patients (cases L1, L2, L4, L6, L7, and L8), and lymphoma was diagnosed by bone marrow examination in four out of six patients.
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