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Conclusion: Bone erosion can be related to AFR.
Recognition of this possibility is important because bone erosion can be interpreted as an indication of invasive pathosis.
Certain drugs can suppress inflammation effectively, but fail to protect against bone erosion, whereas under other conditions, bone erosion can be halted, but inflammation may continue unabated.
Bone erosion can be detected as early as several weeks after the onset of the first clinical signs and symptoms of RA [ 1].
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In RA, bone erosions can progress even when the inflammatory process is adequately controlled (that is, in clinical remission) [ 176], and progress of bone erosions can be halted by denosumab in spite of persistent inflammation [ 133- 136].
A previous study has indicated that MRI synovitis, bone edema and erosion can be detected within weeks of the onset of symptoms [ 6], and of these features, bone edema has repeatedly been shown to be the most important predictor of future erosions at the wrist [ 2- 4].
Finally, the impact of soil erosion can be included.
Telomere erosion can be regarded as a biological clock [ 5].
Subchondral cysts and bone erosions can also be observed in some patients [9], as were seen in case six of this report.
Erosions can be detected on MRI to a comparable degree of reliability as bone marrow edema despite the significant heterogeneity of their appearance on MRI.
CT seems to be even more sensitive than MRI for detection of bone erosions, and can be considered a standard reference for detection of bone erosions in RA [ 12, 22, 23].
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