These data identify a novel molecular mechanisms underlying immune aging by demonstrating that CD137-expressing CD4+ T cells in the bone marrow engage CD137L on hematopoietic progenitor cells, and that this CD137L signaling biases hematopoiesis towards myelopoiesis during aging.
Biomimetic functionally gradient materials have been developed for providing rigid bone-engaging caudal and coronal bioactive surfaces that transition to a flexible fibrocartilage-like portion.
The EGF signalling stimulates the growth of bone metastasis directly by increasing tumour cell proliferation and indirectly by engaging bone stromal cell in metastasis-promoting activities.
In conclusion, studying the complex cellular network engaging bone and immune cells responsible of the pathogenesis of osteoporosis has permitted the individuation of new pathological mediators, mechanisms and pathways.
"No one benefits when people loot dinosaur bones or engage in grave robbing or defacing temples.
The articular surfaces of the ulna, radius and carpal bones are engaged during many activities, such as sport, manual work and musical instrument playing.
Their results indicated that the holding power of screws is directly correlated to bone density, thread design and number of threads engaging the bone.
This means that instead of coming into a pose for a short amount of time and hugging the bones close together by engaging our muscles, [one] needs to pull the skeleton apart non-aggressively and with appropriate pressure and then remain stationary a while, allowing the muscles to remain stretched but without engaging them.
The most important factor in determining press fit cup stability in human THR is the ability of the cup to engage bone around the entire outer periphery [ 15]; however circumferential rim contact is not possible in dogs because the normal canine acetabulum is not hemispherical.
The premise of "The Maze of Bones" is dramatic and instantly engaging: Amy and Dan Cahill are orphans, brother and sister, neglected by their many rich relations.
The chemokine CXCL12 and C-X-C chemokine receptor 4 (CXCR4), to which it binds, form an axis that is a key molecular interaction between HSCs and the bone niche [ 110], and is also engaged in bone metastasis of prostate cancer [ 111].
