Sentence examples for bone destruction compared to from inspiring English sources

Induction of arthritis in WT mice led to severe local joint inflammation, characterized by pronounced cellular infiltration and osteoclast recruitment with associated bone destruction compared to PBS control knees (Figure 1A,B and 2A,B).

Risedronate, alone or in combination with docetaxel, prevented osteolytic bone destruction compared to control, whereas administration of docetaxel alone had no effect.

This certainly seems probable since a recent study has demonstrated that prostate tumours-expressing high levels of Dkk-1 produce more extensive local bone destruction compared to controls that express lower levels (Hall et al, 2005).

As shown in Figure 5A and 5B, arthritic joints treated using medium and high doses showed lower grades of inflammation, synovial membrane thickness, and cartilage and bone destruction compared to those with control protein treatment or treatment with a low dose of immunotoxin.

However, μCT analysis revealed that reduced ABCC5 expression in mouse-derived 4T1 cells resulted in significantly less (shRNA 1, 26% bone destruction; shRNA 2, 16% bone destruction) bone destruction compared with the scrambled controls (40% bone destruction).

They also had less cartilage and bone destruction compared with animals of the sham group, confirming the clinical scoring (figure 2D).

Using intra-peritoneal injection of SFN, the authors demonstrated that this compound ameliorated the effects of CIA with lower degrees of inflammation, synovial hyperplasia, pannus formation, and bone destruction compared with vehicle alone [ 95].

The OVX group treated with DCA had an earlier onset of disease, more frequent and more severe arthritis, and more synovitis and bone destruction compared with the sham-operated group treated with DCA, which had intact estrogen production.

RF-TVA produced more discrete cavities and less native trabecular destruction compared to marked trabecular destruction observed with BK.

These factors stimulate osteoclast-mediated bone destruction leading to increased bone lesions compared to control mice [ 57].

Murine models of human MM treated with Pim inhibitor SMI16a reveal reduced tumor growth, prevention of bony destruction and restoration of bone formation compared to control animals.