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Ankle joints were subjected to X-ray analysis to visualise bone destruction and changes in joint morphology (Fig. 1b, c).
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Orthognathic surgery was not indicated because the patient had severe jaw bone destruction and alveolar bone resorption.
A CT scan showed alveolar bone destruction and an ameloblastoma lesion (Fig. 3b).
They are most often osteolytic, characterized by net bone destruction and suppressed new bone formation.
The delicate balance between osteoclast-mediated bone destruction and osteoblast-mediated bone formation is important for maintaining bone mineral density.
These findings have been described as a disconnection between inflammation and bone destruction and repair.
RA is characterised by peripheral joint inflammation, cartilage and bone destruction and, subsequently, joint deformation.
RA is characterized by synovial inflammation, autoantibody production, cartilage and bone destruction, and extraarticular features.
As the bone destruction and osteoclastic activity was localized to the right tibia and not systemic, our assays may not have been able to detect minor changes in TRACP 5b activity or serum Ca2+ levels.
Osteomyelitis hallmarks consist of progressive bone destruction and the formation of sequestra.
Bid-/ mice display increased inflammation, bone destruction, and pannus formation compared to wild-type mice.
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