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The volume of trabecular bone depends on the coordinated actions of osteoblasts (bone forming cells) and osteoclasts (bone destroying cells).
The proliferating mass of synoviocytes locally invades the cartilage and bone, destroying the joint.
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It continued: "Come with me and visit mothers of dead, injured, gone children — thousands of them — and tell them how you didn't know we supplied the weapons that ripped flesh, broke bones, destroyed lives, destroyed lives".
This is exactly the pattern we see when bodies have been transported a long way by rivers with skeletons being broken up, small bones destroyed and only the most robust parts (here, the top of the skull) surviving and the clear conclusion therefore is that they lived in upland areas.
But, in diseases such as osteoporosis or bone cancer, bone is destroyed more rapidly than at which new bone is made.
The loading information must then be communicated to the effector cells that form new bone or destroy old bone.
As a consequence of cancer expansion, cellular and molecular homeostasis of bone microenvironments is disturbed and bone is destroyed, leading to the development of bone metastases.
The images will show whether a tumour is creating bone tissue or destroying normal bone tissue.
Waves from the explosion, especially in enclosed places like buses or restaurants, reverberate violently through the human body, collapsing lungs, breaking small bones and destroying internal organs.
Higher temperatures, higher concentration, and most organic acids extract variable quantities of the organic components of bone matrix and destroy bone morphogenetic proteins.
Deamination or dinitrophenolation of the epsilon-amino groups, irradiation and other physical agents which produce denaturation of the bone collagen destroy the morphogenetic properties of the bone matrix.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com