Bone defects, such as compressive fractures in the vertebral bodies, are frequently treated with acrylic bone cements (e.g., PMMA).
In conclusion, Sr-forsterite nanopowder could be a promising candidate for bone tissue engineering and reconstruction of bone defects such as osteoporosis.
The improvisation of the treatment procedures for treating the various kind of bone defects such as, bone or dental trauma and for diseases such as osteoporosis, osteomyelitis etc., need the suitable and promising biomaterials with resemblance of bone components.
The most common approaches to repair bone defects, such as the transplantation of autologous and allogeneic bone grafts or substitution of artificial bone, exhibit many disadvantages.
A wide variety of reasons can give rise to bone defects, such as trauma, tumor resection or infection, which has become a challenge in clinical treatment.
Most of these patients (n = 408, 81%) had osteoarthritis as the main diagnosis, 9.5% (n = 48) had other bone defects such as aseptic bone necrosis and malunion/nonunion of fracture, and another 9.5% (n = 48) had a variety of other diagnoses; 11 of the patients of this group had osteoarthritis as secondary diagnosis.
All grade 4 lesions affecting the subchondral bone (osteochondral defects), such as a fissuring or erosion, were correctly assessed on MRI.
The fascia was included into the flap according to characteristics of donor site area and of the defect such as in the case of bone exposure.
The traditional clinical methods of bone defect management, such as autografts and allografts of cancellous bone, can be limited by the large size of bone defects, poor viability of host environment and unpredictable graft resorption (Burg et al. 2000).
Different options are being used to manage acetabular bone defects: techniques such as impaction bone grafting and a cemented cup (according to Slooff et al).
