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Accordingly, our protocol is the first to test the use of bone fragments as an ideal vehicle to transplant such cells residing in the bone core.
f Bone core was taken at 3 months after the socket preservation.
The trend to develop a bone bridge was highest in those animals with the largest epiphyseal bone core and hence the smallest distance between this epiphyseal bone core and the metaphyseal bone (Figure 6).
Histological sections were prepared from a bone core biopsy obtained in an oblique direction from the buccal cortex in one patient at the site of subsequent implant placement.
A bone core was taken from the center of socket preservation sites and histologic sections were prepared at implant placement (Fig. 1f).
5. Figure 6 In the absence of an epiphyseal bone core or at the beginning of its formation (above), and the risk to develop a transphyseal bone bridge is lower in comparison to a situation where the bone core has developed further.
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Bone marrow core biopsies from the same patients were included on the same TMA for comparison.
B5-fixed bone marrow core biopsies were reviewed for areas with the highest concentration of blasts.
Forty-six patients with ALL treated during this time period had evaluable bone marrow core biopsies.
Tumor TMA slides, bone marrow core biopsy samples on slides, and bone marrow aspiration smears were used for conventional immunostainings.
Bone marrow core biopsies were decalcified in ethylene diamine tetra acetic acid for 1 h, then fixed in 10% formalin and embedded in paraffin.
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