Bossini et al. [ 28] investigated the effects of LLLT and Biosilicate (180 212 μm) on bone consolidation in osteopenic rats.
The authors conclude that the docetaxel and Sm-EDTMP regimen used as consolidation in patients with bone metastases from castration-resistant prostate cancer is associated with a high biologic and symptomatic response rate, prolonged survival, adequate pain control, and acceptable adverse effects.
Extensive subgroup analysis echoed the results of the global analysis and demonstrated better overall survival after MAB ch14.18 consolidation in patients without MYCN amplification, patients in CR/VGPR after induction, and patients without residual bone marrow involvement after induction.
In February 2012, because bone consolidation had not occurred, the patient underwent surgical revision to remove the locking plate, clean the wound, and insert an external fixator.
We allowed another 3 months for bone consolidation with REDII removal in the office.
In the rabbit bone defect/lengthening model, local injection of PRP enhanced bone consolidation during the consolidation phase; however, in the early stage of distraction osteogenesis, the combined use of decalcified bone matrix along with PRP did not reveal any additional benefit [ 43].
The study has shown that the use of PGE1 in the postoperative period in the main group resulted in a decreased time to bone consolidation, represented by a faster rate of bone callus formation.
No pain was represented by any patient when walking after regenerate bone consolidation.
However, in an experimental canine model, the bone-healing index showed that new bone consolidation was best with zero-day latency in metaphyseal and diaphyseal lengthening [13].
Bone consolidation within 1 year after surgery occurred in all 16 cases that had been treated with curettage.
