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The trypsin-labile region of bone collagen does not include hydroxyproline, and therefore is different from the trypsin-resistant triple helical portion of the collagen macromolecules [ 35, 36].
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While Urist et al. reported that bone collagen did not shrink with temperatures below 60°C [ 36].
Although calcification occurred as soon as osteoblasts differentiated and new bone matrix was deposited on the surface of the old matrix, the bulk of the old bone collagen did not recalcify.
In bone, type V collagen does not show so specific distribution that type III collagen does.
"Collagen doesn't penetrate," Dr. Rubin explained.
Collagen did not support substantial elastogenesis by SMC.
However, the presence of collagen did not alter lysozyme activity.
Growth of hepatocytes on collagen did not increase transduction efficiency.
In contrast, collagen did not activate these cells.
Since the gene for, say, collagen in bones does not have exactly the same DNA sequence in humans and mice, the collagen produced is not exactly the same, but it functions similarly.
Unlike dentin and bone, enamel does not contain collagen.
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