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Stiffness of the bisphosphonate-enriched bone cement samples was 5%% less during three-point flexural test (p = 0.0087) and about 1 % during the compressive test (p = 0.06).
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A typical load deflection curve for bone cement samples is shown at Fig. 2 and for bisphosphonate-enriched bone cement at Fig. 3.
Biomechanical parameters were determined based on the characteristics from the three-point flexural test and the compressive test, and the densities of the bone cement and bisphosphonate-enriched bone cement samples are shown in Table 1.
Significant changes were observed in the values of transverse Young's modulus, which was about 4%% less in bisphosphonate-enriched bone cement samples.
We pressed bone cement samples in the agar 10 minutes after inoculation, after which the plates were incubated aerobically at 37° C.
We immersed bone cement samples in separate 20-mL volumes of phosphate-buffered saline and two samples of each bone cement were removed after 6, 24, 72, 168, 336, 504, and 672 hours.
The table shows the mean values, standard deviation and the statistical significance level between bisphosphonate-enriched bone cement samples and pure bone cement samples.
We placed a bone cement sample of Palacos R, Palacos R-G, or Copal bone cement into the TSB to allow biofilm formation on the cement samples.
Bone cement was shown to be more effective at treating GCT compared with bone grafting.
Changes were detected when the bone cement was pressurized.
In the second phase, the outer surface of fresh sample blocks for each bone cement was coated with three layers of a commercially available red nail polish.
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