Sentence examples for bone cells in vitro from inspiring English sources

We investigated the effects of BA on murine bone cells in vitro and in ovariectomized (OVx) mice.

As one of the stimulators on bone formation, osteogenic growth peptide (OGP) improves both proliferation and differentiation of the bone cells in vitro and in vivo.

Lipotoxicity has been demonstrated in bone cells in vitro using osteoblasts and adipocytes in coculture.

Whilst not quantifiably established in this study, other studies have demonstrated that LPS affects mineral deposition by bone cells in vitro (5, 33).

Because of the complexity of the bone environment in vivo, several models have been developed to understand the effects of mechanical stimulation on bone cells in vitro.

The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor statin, was the only compound that specifically increased BMP-2 mRNA in bone cells in vitro and subsequent bone formation in vivo.

The cytokine PGE2, a regulator of bone metabolism, is released in response to loading by bone cells in vivo and in vitro, while extracellular mineral deposition, the major inorganic component of bone, is also load-dependent.

Thyroid hormones affect bone cells both in vitro and in vivo by stimulating osteoblast and osteoclast cells with more bone resorption and increased skeletal remodeling [ 27].

In addition to their effects of bone cells, recent in vitro and animal studies have shown that the bisphosphonates also directly inhibit the proliferation and induce the apoptosis of osteotropic cancer cells [ 3- 8].

However, bone cells cultured in vitro are responsive to a variety of different mechanical signals including fluid flow and shear stresses.

We report that SFX-01® SFX-01®s bone mimprovesitecture in vivo, produces corresponding changes in bone cell behaviour in vitro and leads to greater symicroarchitectureinhout marked effects on cartilage lesion sevivoty in STR/Ort osteoarthritic mice.