Sentence examples for bone breach from inspiring English sources

In OA, new blood vessels from the subchondral bone breach the tidemark into cartilage [ 12], and it is thought that these blood vessels contribute to articular cartilage ossification [ 13] and lead to osteophyte formation around the cartilage [ 14].

Washington has made little secret of its European Nato allies cutting their defence budgets to the bone – breaching the 2% of GDP target – before and after the 2008-09 bankers crisis.

In the pathogenesis of OA, nerves grow into joint structures through vascular channels mainly from subchondral bone breaching through the tidemark.

Imaging data revealed that the SBC originate in the presence of a subchondral bone plate breach, with evolving composition over time.

For osteochondral defects, the subchondral bone plate is breached leading to an inflow of blood containing bone marrow-derived mesenchymal stem cells (BMMSCs) that populate the defect site (Khan and Scott 2009; Madry et al. 2011).

Another line of research would be to determine the feasibility of implanting a remedy in the bone marrow, or breaching the bone marrow barrier for a period to allow full combat by the immune system.

These findings suggest a mechanism for bone loss without breaching the cortical plate, where bone edema might be followed by a subchondral bone defect, which could in turn precede the development of erosion.

This cascade further facilitates PCa cells to breach the bone endothelial layer (transendothelial migration; TEM) to establish micrometastases in the bone microenvironment (Barthel et al, 2013).

Microfracture and subchondral drilling breach subchondral bone to allow migration of cells and chemical mediators into defects [ 6].

Regarding the use of a clinically relevant animal model for cartilage repair, it is difficult to create a chondral injury which does not breach the subchondral bone in small animals such as rabbits, rats, and mice due to the limited thickness of their articular cartilage, and therefore, these conditions may not be as clinically relevant as would be obtained with the use of a larger animal.

Yet it should be done cautiously to not breach the cortical bone.