Sentence examples for bone at the joint from inspiring English sources

In addition, bone at the joint margins is markedly active since is the site of osteophyte development in OA.

The breakdown and deterioration of cartilage leads to the formation of new bone at the joint surfaces (sclerosis) and margins (osteophytes) [ 2].

Rheumatoid arthritis (RA) is a common inflammatory rheumatic disease characterized by synovitis and by development of cartilage destruction in the joints, erosions in the subchondral bone at the joint margins and by periarticular osteopenia adjacent to inflamed joints [ 1, 2].

The progressive destruction of the structural components of the joints involving the articular cartilage, the bone at the joint margins, as well as periarticular and subchondral bone, is another hallmark in the progression of RA.

In diseases such as osteoarthritis (OA) and rheumatoid arthritis (RA), degradation of the ECM exceeds its synthesis, resulting in a net decrease in the amount of cartilage matrix or even in the complete erosion of the cartilage overlying the bone at the joint surface.

He described, with way too much relish and in clinical detail, how the right hand of convicted thieves would be amputated by a surgeon, peeling back the skin of the wrist, then separating the bones at the joint.

Unlike the situation in RA patients, many arthritis models show bone erosion but also pronounced new bone formation at the joint margins.

Osteoarthritis (OA) is a common disorder of synovial joints characterized pathologically by focal areas of damage to the articular cartilage, centered on load-bearing areas, which is associated with new bone formation at the joint margins (osteophytosis), changes in the subchondral bone, variable degrees of mild synovitis, and thickening of the joint capsule [ 3].

Other hallmarks of the disease are new bone formation at the joint margins (osteophytes), limited inflammation (synovitis), and changes in subchondral bone structure (sclerosis).

However, by sampling the IT region we have avoided secondary pathogenic changes that the subchondral bone undergoes at the joint as the disease progresses (such as sclerosis, osteophytes and cysts), which could confound identification of altered gene expression potentially responsible for the underlying subchondral bone remodelling.

Primary OA was defined by deterioration and abrasion of articular cartilage (joint space narrowing) or formation of new bone (osteophytes) at the joint surface of the knee (medial tibio-femoral, lateral tibio-femoral or patello-femoral), demonstrated on a radiological examination carried out within the previous 3 months [ 9].