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The results demonstrated that the scaffolds with engineered macroscopic channels and a porosity gradient had higher percentages of new bone area, compared to scaffolds without engineered channels.
TG females were more susceptible to loss of BMD, BMC and bone area compared to WT mice when measured as the percent change from baseline.
Similar(58)
Microporous HA scaffolds revealed four times more bone ingrowth and seven times higher bone contact area compared to the ZrO2 scaffolds.
Quantitative histomorphometric measures of defect cross sections show that, along the axis least able to resist bending loads (minor centroidal axis, CA), bone laid down in the first two weeks after surgery exhibits more mineralization albeit less total area compared to bone along the axis most able to resist bending loads (major CA).
Other authors suggested that rat ovariectomy plus calcium deficiency results in a great decrease of bone volume and cross-sectional area compared to the calcium alone [ 27].
PCL noncoated and PCL coll I/cs coated scaffolds showed significantly more (43.3 and 47.1%) new bone formation within the defect area compared to the empty defects (26.6%) after 6 months.
The PCL coll I/cs coated scaffolds showed a more homologous new bone formation across the whole defect area compared to the PCL noncoated implants.
Newly formed bone was present in a much larger area compared to all groups without BIS.
Micro-CT analysis of the tibiae revealed that Hdac4−/− mice have significantly decreased cortical bone area compared with the wild type mice.
Those with cysts had less lateral tibial cartilage volume and greater tibial plateau bone area compared with those who did not have a cyst (Table 1).
Those who were obese (BMI ≥30 kg/m) also had greater medial tibial bone area compared with normal weight subjects [ 16].
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