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After 12 weeks, the OVX + DPEMF group presented better efficacy in prevention against OVX-induced bone loss and deterioration of trabecular bone architecture compared with the OVX + NPEMF group.
As illustrated in Figure 1B, OVX caused a significant deterioration of trabecular bone architecture compared with the Sham-control group (P < 0.01).
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We also explored a different connection architecture compared with previous work.
In order to justify the newly proposed approach, the measures of complexity of the bone architecture were compared with the results of traditional 2D bone histomorphometry.
The ACPA-positive individuals exhibited significant alterations in cortical bone architecture as compared with the ACPA-negative individuals.
GnRH-a suppressed uterine weight, decreased osteoblast proliferation, bone strength, trabecular bone volume and architecture compared to control.
OVX-NS rats showed marked improvement with preserved bone architecture as compared to OVX rats.
Furthermore, SHG images clearly disclosed the disturbed and somewhat haphazard organization of the bone collagen fiber bundles in arthritic bone compared with the better organized lamellar architecture of the healthy control bone.
The pattern of much lower levels of G ¯ with the low-unequal architecture, compared to the other three genetic architectures, was the same for all estimation methods.
Model simulations in the three architectures are compared with measurements.
Finally, a more clinical approach consists in comparing bone architecture in patients with osteoporotic fractures and in controls matched on bone mass.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com