These abnormalities disrupt normal bone architecture and lead to various complications such as bone pain osteoarthritis, pathological fracture, bone deformity, deafness, and nerve compression syndromes.
The abnormal bone turnover disrupts normal bone architecture and causes bone pain, bone deformity, deafness, osteoarthritis, and pathological fractures [ 2].
Paget's disease of bone (PDB) disrupts normal bone architecture and causes pain, deformity, deafness, osteoarthritis, and fractures.
This disrupts normal bone architecture and causes pain, deformity, deafness, osteoarthritis, and fractures.
Treatment with MTX in combination with CF101 was associated with normal cartilage and bone architecture, and with an histological score that was almost zero.
When stress and/or strain deviate from the normal range, the remodeling process leads to adaptation of the bone architecture and its degree of mineralization to effectively withstand the sustained altered loading.
Inhibition of TβRI function increased bone mass and multiple aspects of bone quality, including trabecular bone architecture and macro-mechanical behavior of vertebral bone.
These mice showed increased bone mass and multiple aspects of bone quality as trabecular bone architecture and macro-mechanical behavior of vertebral bone [35].
PDB is characterized by focal increases in bone turnover, affecting one or several bones, and resulting in abnormal bone architecture and weakened bone strength (Michou et al. 2006).
Preoperative cervical CT is useful for bone architecture and surgical planning.
