Sentence examples for bond replacement from inspiring English sources

We demonstrate that disulfide bond replacement is an efficient strategy for engineering therapeutic peptides.

Therefore, important considerations in selection of an amide bond replacement are the potential of the surrogate to mimic both the steric and electronic properties of the amide bond.

Five different chemistries for peptide bond replacement have been employed and the resulting five individual sublibraries tested with the HIV PR and its drug-resistant mutants.

Because the β-phosphate can rotate around the α-β bridging bond, replacement of one β-oxygen atom by sulfur leaves two more oxygen atoms on the β-phosphate available for coordination of Mg2+.

Elba has long been rumored to occupy a place on Sony Pictures' short list of Bond replacements, which saw its stature grow recently with the leaks of a series of Sony emails late last year.

In the ether lipid metabolism pathway, a unique biochemical reaction is catalyzed by the enzyme alkylglycerone phosphate synthase (alkyl-DHAP, EC 2.5.1.26) resulting in the formation of the ether bond by replacement of the sn-1 fatty acid with a long chain fatty alcohol (Figure 5).

This is consistent with previous studies showing an ∼2 kcal/mol loss of B-DNA stability from a single G·C to I·C substitution and could be explained by the loss of a single N H···O bond or replacement of the N H···O bond with a weaker C H···O bond.

Randy Winn, Bonds's replacement in left field Saturday, made back-to-back spectacular catches in the top of the ninth to keep the score tied.

However, in line with its postulated importance in a hydrogen bond network, the replacement of Ser47 with a threonine resulted in no significant change in kinetic parameters for the enzyme.

Gavezzoti pioneered this field by essentially ignoring long-range diffusion process and exploring the manifold of solute solute contacts from small model systems comprised of only a few solutes.[ 42, 43] This allows focusing molecular simulation to the critical issue of solute solvent bond dissociation and replacement by solute solute bonds.

A two-step system involving the surgical implantation of titanium fixtures titanium bonds to human bone and the later attachment of replacement teeth has also been developed.