"People were coming together and taking on really bold problems".
Acknowledging this problem, BOLD has a more selective set of submission criteria [27] and has the advantage of using global alignments whereas BLAST uses local alignments.
These were bold moves, but the problem for both leaders is that both sides in Congress still believe their partisan arguments will ultimately win out and perhaps enable them to sweep the next election.
During his campaign for the presidency in 2002, he offered a bold solution to the problem every South Korean leader had deplored but failed to fix: the strangling congestion of Seoul and its surrounding towns, which house half the country's 49 million population.
Early days, he kept saying, no problem, a bold display of a stiff upper lip.
Fixing the problem requires bold, even controversial, measures.
Solutions already exist, but the scale of the problem requires bold and resolute action.
It is a bold move toward public problem-solving on a global scale.
On Friday, for instance, he called on Mr. Gore to muster the courage to propose "bold solutions to big problems".
With the support of a new president who says he wants to tackle tough problems with bold solutions, we just might get the rail service we need.
