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But the direction and self-direction of those figures is more daring — in cinematic invention and in emotional revelation; they also appear to peel away, with those bold mechanisms, layer after layer of pretense and defense, until they fuse onscreen with their own visions of horror and self-loathing.
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The president's senior adviser on the Millennium Development Goals, working with the National Assembly, has been leading a bold mechanism to transfer federal funds to state and local governments in a robust and accountable manner.
First, they are remarkably substrate-specific in spite of their "bold" reaction mechanism, in which a highly reactive flavin-C4a-OOH intermediate is generated even in the absence of a waiting substrate.
Thus far, positron emission tomography (PET) and current functional MRI (based on the Blood Oxygen Level Dependant or BOLD contrast mechanism) have relied on the principle that neuronal activation and blood flow are coupled through metabolism, and brain activation can be indirectly imaged through variations in local blood flow.
In addition to the BOLD effect, other mechanisms are supposed to contribute to the endogenous MR contrast.
The inferred rupture plane is shown in bold on the focal mechanism.
While the neuronal mechanisms behind negative BOLD signals in humans are not well understood, animal data seems to indicate that it could reflect neuronal inhibition [25].
These studies have significantly advanced our knowledge of the neurometabolic and neurovascular mechanisms that underlie BOLD.
Further studies are warranted to get additional insights into the mechanisms underlying muscle BOLD signal alterations in patients with SSc.
In summary, our study demonstrates the sensitivity of BOLD fMRI to detect the mechanisms underlying treatments of known efficacy in OA.
TO2 signals are driven by the same neurovascular mechanisms as the BOLD signal and therefore provide a close hemodynamic surrogate, via intracerebrally implanted carbon paste microelectrodes (13 16).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com