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Discordant Plus (D+): Some clusters of significant IED-related BOLD signal change were localized within the SOZ, with other significant BOLD clusters in other lobes.
It's made of a stretchy nude mesh fabric, with bold clusters of printed faces outlined in black.
DCM of fMRI can thus provide information about the directionality of functional relations between positive or negative BOLD clusters and is context-dependent [72], [73].
In all 4 patients, there were IED-related BOLD clusters outside the icEEG coverage.
In one patient, some remote BOLD clusters matched regions of hyperperfusion revealed by ictal single-photon emission computerized tomography (SPECT).
The locations of the icEEG electrodes and BOLD clusters were verified at operation and by inspection of the EPI data, respectively.
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In Patient 2, a single BOLD cluster colocalized in part with the IZ, which was extensive on icEEG, but remote from the SOZ.
In Patient 23, a single BOLD cluster was revealed deep in the (widespread) IZ but remote from the SOZ, which was presumed to lie outside the region covered by icEEG.
28 We therefore limit ourselves to an anatomical description of the IED-related BOLD cluster and the SOZ and an allowance of 2cm to account for displacement in particular.
BOLD-clusters were assessed individually for anatomical localization.
BOLD-clusters were assessed for anatomically correct sensorimotor localization.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com