The silent mutations used to prevent re-cutting by Cas9 are underlined, whereas the bold and underlined sequences are the ssODN donor template sequences that were successfully introduced into Rag2 locus.
And then, bold and underlined, "Please do not steal my joke.
Microsoft's program was the first to make extensive use of the computer mouse, to display styles on-screen (italic, bold, and underlined text), and to feature style sheets and multiple windows (i.e., separate work spaces for editing multiple documents).
The mutated base is in bold and underlined.
The instances of lexical metaphors are presented in bold and underlined.
The sequence in bold and underlined corresponds to the region where the BS35S-F primer was designed.
The matched amino acid residues that exhibited 69% coverage to the native S. oneidensis FadR are given bold and underlined type.
Figures in bold type defines values significantly lower than the control group (THR), whereas the bold and underlined values are significantly higher than the control group (THR).
XB21 also contains another Phe-x-Asp/Asn-x-Phe (FxD/NxF; x is any amino acid) motif within the short conserved segment at the N terminus (bold and underlined) (Fig. 1a; Additional file 1: Figure S1).
Cooper David Aaker Smith is a young philanthropist, a title that is printed in bold and underlined on his resume (that his parents painstakingly wrote for him).
Everything I wrote last week has now been printed bold and underlined, "never overestimate the intelligence of the American public", and "give them what they want, and they'll watch it".
