Note that the effects of ZEB1 haploinsufficiency with either diet occurred during a limited period or weight gain, when total body weights were increasing from about 20 to 27 grams and was thus not related to age of the animals as much as to actual body weight.
This appears suggestive of altered lung development, although this conclusion must be moderated by the observation that all specific values, i.e. when reported to body weight, were increased.
At the end of the dietary period, their body weight were increased compared to that of chow-fed animals (chow, 28.2±0.4; high-fat, 30.5±0.8; high-fat/fish oil, 33.4±0.8 g, p<0.05 high-fat vs. chow and high-fat/fish oil vs. high-fat).
This time the act seemed to take on an unusual gravity, as if on Jupiter, where his body weight was increased and the desire pressed down by lethargy and inertia.
Its body weight was increased by about 30 to 40% when raised on the N-enriched plants.
The body weight was increased as well, ranging from 25 39% (fig. 2B, p<0.001).
Moreover, the ratio of the soleus weight reported to the total body weight was increased by 13% (Table 1).
Body weight was increased after 7 weeks on both obesigenic diets (44.6±0.65, 39.8±0.63, and 28.6±0.63 g for EN, HF, and C groups, respectively) and resulted in elevated concentrations of serum insulin, glucose, and leptin and lower serum triglycerides.
In fact, after 5 months of HFD feeding, the caloric intake per total body weight was increased by 40% in HSL null mice compared to wildtype littermates (data not shown).
