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At 3 months of age, both C and LP animals fed the OB diet after weaning presented a significant increase in body weight when compared to usual chow fed mice but no influence of maternal diet was found (Table 1).
As a consequence of forced catch-up growth during lactation, LP pups presented at weaning a higher body weight when compared to C (C: 10.94±0.82 vs. LP: 13.41±0.62 g; N = 12 litters/group, P<0.05).
The reasons for this poor performance on open field behavioral activity after arginine butyrate treatment are unclear; however, the positive behavioral effects seen with combination group were likely influenced by their reduced body weight when compared to the saline-treated mice.
Acarbose even seems to be superior in decreasing body weight when compared with the insulin-neutral treatments, metformin and vildagliptin.
MOG35-55 did not alter body weight when compared to CFA controls (P = 0.3; Table 2; Figure 3C).
Seven of the 27 conceptuses in the ART group were in the > 97th percentile body weight when compared with controls.
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With respect to changes in body weight, the recombinant-human-GH group showed the highest increases (+9.9±2.0%) in body weight when comparing body weights at the start of the treatment and after the last injection (Fig. 5).
As shown in Table 1, S. muris-infected rats of group (GII) had significant reduction in their body weights when compared with the uninfected control group (P = 0.0004).
Furthermore, rosiglitazone-treated mice had generally higher mean body weights when compared to untreated mice, as expected.
Although diabetic animals on normal diet gained weight after 8 weeks (18% increase), they gained less weight than control animals (35% increase) and had significantly lower body weights when compared to controls (Table 1).
There were no significant differences in body weights when comparing knock-out and wild-type mice.
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