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After the induction of diabetes, differences in body weight of normal and diabetic rats were observed (p < 0.01).
In our study, Figure 1 shows the changes in body weight of normal and streptozotocin-induced diabetic rats.
At the end of 28 days treatment, the body weight of normal rats, diabetic control, different doses of MM leaves extract and glibenclamide treated rats were observed.
All animals were subcutaneously administered 4 mL/100 g body weight of normal saline after the surgery and once a day thereafter.
Animals in the model and treatment groups were treated with 5 ml/100 g body weight of normal saline subcutaneously at the completion of surgery to provide replacement for the extracellular fluid sequestered during peritonitis.
However, after six weeks of treatment with GH or GH and T4, the df/df mice were significantly larger than saline treated mutants (p < 0.0001) and matched the body weight of normal mice.
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The body weights of normal, normal treated, diabetic treated and glibenclamide treated group, increased significantly by +25.8 g, +31.6 g, +24.1 g and +21.2 g respectively, whereas the body weights of diabetic control group decreased by −33.3 g (Table 3).
By the end of the experiment, the body weight of the normal control group was significantly increased (p < 0.001).
Young male Ames dwarf mice treated with a combination of GH and T4 exhibited a major increase in bodyweight, approaching the body weight of their normal siblings.
This is most pronounced in the Snell and Ames dwarfs that, in adulthood, weigh less than a half of the body weight of their normal siblings.
Body weight of mice on normal and high-fat diet were taken.
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