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Administration of Ac-PLP-BPI-NH2-2 an an s.c. solution produced clinical scores and maintenance of body weight comparable to i.v. solution, but with reduced overall survival, presumably due to anaphylaxis.
At 12 weeks of age on the chow diet, BALB.apoE-/ mice had a body weight comparable to B6.apoE-/ mice (18.9 ± 0.7 vs. 17.6 ± 0.9 g; P = 0.30).
Male rats treated with vehicle (for DES) showed a profile of increasing body weight comparable to that of intact control animals.
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Ehd3 /– mice were born at expected Mendelian ratios, were healthy and fertile with body weights comparable to their wild-type littermates (Figure S1D & S1E).
Mice receiving Rapatar maintained a healthy appearance with physical activities and body weights comparable to the control mice (Fig. 1C).
Chronic administration of BI 186908 resulted in significant body weight reduction comparable to sibutramine in a 4 week diet-induced obesity model in rats.
Estimated heritabilities for starting body weight were comparable to previous estimates in turkeys [ 7, 11].
Their body weight is comparable to that of their wild-type littermates.
However, mice treated with 50 mg/kg NS-018 progressively gained more weight than vehicle-treated mice, and their body weight was comparable to that of WT mice.
Their body weight was comparable to the one of control rats at 14 weeks and lower at 21 weeks (p < 0.01).
At lower concentrations, female body weights were comparable to controls, whereas male body weights at 1,000× were significantly reduced only 1 week postweaning.
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