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Echocardiographic myocardial mass was calculated with the Penn-Cube formula 21 and indexed to the body surface area: Standard 12-channel ECG for the measurement of PQ time, QRS time and Sokolow-Lyon index were digitally recorded using clinical electrocardiography platforms and analysed automatically.
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However, in patients with glomerular hyperfiltration and with extensive burns over more than 15% of their body surface area, higher than standard daily dosages of aminoglycosides may be needed to reach adequate Cmax [ 42].
GFR-inulin data were corrected for a standard body surface area of 1.73 m.
In order to evaluate the differences between individuals, GFR was compensated using the standard body surface area of Japanese, 1.48 m, and was estimated as 24-h Ccr × patient's body surface area/1.48.
The ratio of graft size to standard liver volume (from body surface area) of the recipient should be over 50%[30]]; alternatively the ratio of graft size to body weight of the recipient should be over 0.8 1.0%.
Since previous trials did not specify body surface areas, we based comparisons of dose intensities on a standard of 1.75 m body surface area, which corresponded to a woman with an average weight of 68 kg and an average height of 165 cm.
Data are presented standardized by body surface area.
All renal hemodynamic parameters were standardized to body surface area.
Otherwise, DO2I was calculated by the application of the standard formulae and indexed to body surface area.
In one such trial, tremelimumab was administered at a dose of 15 mg/kg every 12 weeks while high-dose interferon was administered concurrently in standard doses, involving 20×10 U/m of body surface area for 5 days a week, followed by maintenance interferon at a dose of 10 × 10 U/m of body surface area subcutaneously 3 times a week for 8 weeks.
†For descriptive statistics, data are mean (standard deviation) for continuous predictors (age and body surface area), and number (percentages) for binary predictors.
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