Sentence examples for body surface area normalization from inspiring English sources

Reagan-Shaw et al. ([2007]) suggested to use body surface area normalization for dose translation from animal to human studies.

The dosage of probiotics used in the study was based on the body surface area normalization method from the recommended human dose from VSL#3 (Reagan-Shaw et al. 2008).

This dose converts to 1.6 4.1 mg/kg of human equivalent dose (HUD) based on body surface area normalization (BSA) method [43], and translates to a single dose of 96 246 mg in an average individual of 60 kg, which seems to be safe and acceptable dose based on several previous studies in humans mentioned above.

Conversion of doses from mice to human is achieved using a formula based on body surface area normalization (Reagan-Shaw et al., 2008).

This dose corresponds to the human equivalent of 16 mg/kg, according to the body surface area normalization method for conversion of drug doses between species as recommended by the Food and Drug Administration (Reagan-Shaw et al, 2008).

Our calculation of the human equivalent amount of American ginseng consumed by mice uses the body surface area normalization method (11) with the following assumptions: a typical mouse eats 3.5 g chow daily and weighs 22 g; the average adult human weighs 60 kg.

Others [ 74– 76] provide evidence that the overestimation of SUVBW of liver tissue in heavy oncological patients can be prevented using BSA (body surface area) as normalization factor.

The gemcitabine dose of 50 mg/kg twice weekly is equivalent to a human dose of 300 mg/m using a body surface area (BSA) normalization method; this is relatively low compared to the standard human dosing regimen of 1000 mg/m given once per week for 7 weeks [ 29- 31].

The aim of the present study was to determine if our trace element supplementation policy for adults adapted to total body surface area would achieve normalization of plasma concentrations of trace elements in burned children.

In 15 CDDP-sensitive nodules, there was no correlation between the administration dose of CDDP and the area reduction rate of HCC either with normalization or without normalization by body surface area as shown in Figure 2a and b, respectively (P = 0.17, r = 0.37 or P = 0.11, r = 0.43, respectively).

Aortic root dimension was compared between the groups after allometric normalization for body surface area (BSA).