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aAssessed only in patients with at least 3% body surface area at baseline.
No correlation was found between Pt AUC1 3 years and weight, BMI and body surface area at the start of chemotherapy.
In RAPID-PsA, the PASI and PASI75 response were assessed in the subgroup of patients with psoriasis involving at least 3% of body surface area at baseline.
Irinotecan is currently prescribed, using a patient's body surface area, at doses derived from clinical trials based on outcomes across populations; this approach does not account for interindividual differences.
The mean TERs from 99mTc-MAG3 were 251 ml/min, 179 ml/min and 152 ml/min/1.73m body surface area at baseline, 1 year after therapy and 2 years after therapy, respectively.
CrCl was obtained daily from 24 h urine collection as a normal procedure in our ICU and normalised to body surface area, at the beginning and during vancomycin therapy [ 10, 13, 16].
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Skin assessments were restricted to patients with at least 3% body surface area involvement at enrollment.
Only patients with at least 3% body surface area involvement at enrollment in ADEPT were included in the analyses of psoriasis area and severity index (PASI) and dermatology life quality index (DLQI).
Randomization was centrally stratified by methotrexate use (yes/no) and extent of psoriasis (< 3% or ≥3% body surface area (BSA)) at baseline.
25– 28 We have reported previously on the treatment of MPM with a combination of surgical debulking with intraoperative heated intraperitoneal chemotherapy and catheter-administered outpatient IP chemotherapy, including cisplatin dosed by body surface area (BSA) at 100 mg/m.
Note that in the clinical trials, PASI scores at follow-up were reported for patients who had ≥3% body surface area (BSA) involvement at baseline or a PASI score ≥2.5 at baseline.
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