The result is an apparent autoinhibition at high dimerizing ligand concentrations because the ligand binds to both monomers and prevents three-body complex formation.
The homology model of the IL-3:receptor complex generated in this study provides a molecular framework to analyze a large body of mutagenesis data on the roles of specific residues in IL-3:receptor complex formation and function.
In this paper, however, we can neglect the effect of GW/P-body formations because the reaction rate mentioned in Ref [ 26] is for the overall siRNA-mRNA complex formation reaction and should already incorporate the effects of this compartmentalization.
Complex formation with n.c.a.
(C) TGF-β-induced FoxO3-Smad2/3 complex formation.
Smaller amounts resulted in incomplete complex formation.
The complex formation is fast and efficient.
Upon complex formation, N1 rearranges for proper complex formation and active site optimization.
Furthermore the complex formation does not involve Sp4 factors.
CAND1 allows the complex formation between CUL1 and SKP [47].
Second, Sro7p acts to promote SNARE complex formation.
