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Immunological changes associated with aging play a major role in both the blunted responses to infections as well as to vaccines intended to prevent many of these infections.
Since depressive patients have been shown to have blunted responses (i.e., lowered AUCi) relative to healthy controls [62, 63], this finding may indicate that physical activity was beneficial in moving the CAR to a more healthy profile.
The blunted responses to acetylcholine and sodium nitroprusside in the fetuses at 0.9 gestation among the group of dietarily restricted ewes (restricted diet of 50% group) were indicative of impaired vascular smooth muscle sensitivity to nitric oxide.
For example, a putative genetic deficiency in 5-HT synthesis in mice [122] [124] may be associated with blunted responses to citalopram [56], [125].
Therefore, the blunted responses of the cocaine smokers could have been even more suppressed if they would have been abstinent for nicotine prior the study.
The more blunted responses as pregnancy progresses protect the fetus and mother from adverse health consequences [ 37, 48, 111].
Similar(46)
In both the non-linear and frequency domain analyses, patients presented a blunted response to tilt.
However, serum IL-10 showed a blunted response to exercise in fibromyalgia [26].
Most diseases are accompanied by a blunted response to acetylcholine but the opposite is true for CFS.
On the contrary, in patients with fibromyalgia, plasma IL-10 showed a blunted response and IL-8 seem to decrease [26, 45].
The present study was designed to test the hypothesis that a decrease in l-arginine bioavailability could be involved in this blunted response to exercise training.
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