Sentence examples for blot the activation of from inspiring English sources

To further characterize the intracellular pathways involved in the cell death induced by MPP+, we examined by fluorimetric assays and Western blot the activation of caspase-9 and caspase-3 after incubation with MPP+ in the presence or in the absence of pre-treatment with LiCl and kenpaullone (Figure 3).

In order to better characterize the multinucleated cells formed in response to IL-32, we investigated, using Western blot analysis, the activation of downstream signalling pathways.

Western blotting confirmed the activation of effector caspase-3 and inactivation of PARP-1 (involved in DNA repair) [24] during the execution of apoptosis in SKOV-3 cells following Fe-SP treatment.

Following HNTMB treatment for 24 h Western blotting confirmed the activation of effector caspase-3, -7 and inactivation of PARP-1 (involved in DNA repair) in SKOV-3 cells (Fig. 5A).

Following HNTMB treatment Western blotting confirmed the activation of effector caspase-7 and inactivation of PARP-1 (involved in DNA repair) in all three cell lines by 0.4 μM of either non-complexed HNTMB or when complexed with Cu II) (Fig. 7E).

In the present study, the serum levels of C3 and its fragments C3a were over-represented in diabetic serum by western blot analysis, indicating the activation of complement system.

We further investigated the expression of iNOS and COX-2 by western blot analysis, and the activation of NF-κB by EMSA in each ear punch biopsies.

Western blot analysis confirmed the activation of STAT-1, STAT-3, and STAT-5 signaling pathways following coculture of lupus CD8+ T cells with UC-MSCs.

The effects of 5-Aza-2'-deoxycytidine (5-Aza-CdR) on the viability and the apoptosis of the androgen-dependent (LNCaP) and androgen-independent (PC3) cell lines were examined by MTS assay and western blot analysis for the activation of caspase-3.

We also used Western blotting to determine the activation of caspases in H1299 cells treated with empty vector, empty vector plus cisplatin, NPRL2, or NPRL2 plus cisplatin (Figure 1B).

In accord with the western blotting results showing the activation of ATM in Asc-deficient IMR90, addition of the same ATM inhibitor to these cells increased the replication-inhibitory effects of Cr VI).