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Dynamic [11C]PBR28 PET imaging data with arterial blood sampling were acquired to quantify TSPO levels as [11C]PBR28 V T. Scans were acquired at three timepoints: baseline, immediately post-drug, and prolonged post-drug.
In addition, [C]CB184 and [C]PK11195 PET scans with arterial blood sampling were acquired to generate input for pharmacokinetic modelling.
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During this time, continuous arterial blood sampling was acquired using an online BGO detector and automated pump at a rate of 5 ml min−1 to measure the arterial input function (Ranicar et al, 1991).
This retrospective study has the principal limitation that no blood samples were acquired.
Arterialised-venous blood samples were acquired at 45 min and 2 and 4 h time-points post tracer injection [33].
Arterial blood samples were acquired during the first 90 min, and both the plasma- and whole blood volume-corrected tracer contents were measured using the well counter.
Blood samples were acquired to evaluate hormonal concentrations, and premenstrual symptoms were assessed through daily record of severity of problems questionnaires.
Blood samples were acquired from patients of the University of California at Davis William R. Pritchard Veterinary Medical Teaching Hospital.
All blood samples were acquired before any therapeutic intervention.
Overnight fasting blood samples were acquired for laboratory measurements.
Peripheral blood samples were acquired before and after mammography.
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