Blood sampling for determination of FDG plasma concentrations in the current study eliminated spillover effects on the late phase of the arterial input function; the validity of this method has been shown before [8].
Techniques and time points of blood sampling for determination of blood gases, arterial lactate, electrolytes, hemoglobin, platelets, white blood cell count, serum creatinine, total bilirubin, creatine-kinase, troponin, plasma IL-6 andTNF-α are described in Additional file 1.
The most accurate means of measuring blood loss is venous blood sampling for determination of hemoglobin concentration; however, such methods have not been broadly adopted because they are neither practical nor affordable in most clinical settings [ 39].
Measurements of postprandial capillary blood glucose concentrations and blood sampling for determination of insulin in plasma were performed over 3 h at 15, 30, 45, 60, 90, 120, 150 and 180 min after ingestion of the test food.
Within the two study populations of blunt and penetrating trauma, subjects were allocated to two groups for pharmacokinetic analysis, one group to frequent blood sampling and another to sparse blood sampling for determination of FVII coagulant activity assay.
Safety assessments (blood sampling for determination of antibodies, physical examinations, vital signs) were performed within 24 hours of chemotherapy in each cycle (day 1) and at the end of the study.
Participants provided a blood sample for determination of a fasting lipid profile and systemic inflammation; blood glucose levels were determined immediately (FreeStyle Flash Blood Glucose Monitoring System, Abbott Laboratories, Abbott Park, Illinois, USA).
Resting blood samples (for determination of glucose, insulin, and leptin concentrations), body condition scores, feed information, and health history were collected from 366 privately owned horses.
Blood samples for determination of BNP, cTnI, and C-reactive protein levels were obtained at hospital discharge and the 1-month, 3-month, and 1-year follow up visits.
Blood samples for determination of total thyroxine (TT4), free thyroxine (FT4), total triiodothyronine (TT3), thyrotropin (TSH), reverse triiodothyronine (rT3), Keto and ASA concentrations were taken during each treatment period on days 0, 1, 3 and 7.
