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For the initial study of linkage disequilibrium, blood samples were selected from 100 patients who presented in 1999 with uncomplicated malaria, having acquired infection in the Thai-Myanmar border region.
A total of 1337 participants with eligible blood samples were selected in 2010 2011 for proANP measurement.
At the same time, control blood samples were selected entirely at random from donors to the Scottish National Blood Transfusion Service (mean age of donors is 42 years), and DNA was extracted as described (Tomescu et al, 2001).
A total of 803 individuals diagnosed with invasive breast cancer and with available blood samples were selected for GWAS genotyping in an independent GWAS looking at overall breast cancer risk [ 26].
Whole genome sequencing (WGS) data for six ovarian serous cystadenocarcinoma and matched somatic control (whole blood) samples were selected from The Cancer Genome Atlas (TCGA) data portal [ 23] using dbGAP in BAM file format.
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Indeed an EBV coverage equal to 0 might indicate blood derived DNA, while LCL samples were selected among those with the highest EBV coverage (in this case, higher than 400).
Principal components (PCs) that exhibited differences between the blood, normal tissue, and tumor tissue samples were selected for further analysis.
Some required blood sample examination, and half of these blood samples were randomly selected for this study because we could not evaluate all of them.
Blood samples were randomly selected from participants who donated blood between 1996 and 1998, with a blood volume of greater than 1.5 ml, from all African-Americans and from all cases with in situ breast cancer [ 17].
For each identified cancer case, control subjects with available blood samples were randomly selected from all cohort members who were alive and free of cancer (except nonmelanoma skin cancer) at the time of diagnosis of the case patient.
Blood samples were collected at selected time-points up to 48 h after dose.
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