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Patients with a QDA-positive or QDA-negative test from their blood sample were defined as having a positive or negative CTC status, respectively.
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Critical aspects of blood sampling are defined including the impact of the test population and sampling conditions on the performance characteristics of IGRA.
The day of first blood sampling was defined as day 1.
Season of blood sampling was defined as Winter: December February; Spring: March May; Summer: June August, or Fall: September–November.
Blood samples were collected to define hematologic and biochemical DLT.
We achieved a control group including 10 healthy volunteers (aged from 35 to 66 years), whose blood samples were withdrawn once, to define the cutoff value for each cytokine.
Fasting blood samples were obtained under conditions of metabolic stability, defined as no episode of diabetic ketoacidosis during the previous month.
Paired blood samples were obtained when the patients were hemodynamically stable (defined as a normal blood pressure, heart rate, and no evidence of peripheral perfusion problems).
Blood samples were obtained from 18 healthy controls (HC) and 29 cirrhotic patients (CA) as defined by clinicoradiological criteria.
First, defining diabetes would be more reliable if the fasting blood samples were collected.
Blood samples were drawn.
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