Cut-offs for 95th percentile blood pressure were based on age- and gender stratified population data [ 27].
These definitions for elevated blood pressure were based on diagnostic criteria from the Joint National Committee (JNC) on prevention, detection, evaluation, and treatment of high blood pressure [ 20].
In particular, we could not determine if changes in blood pressure were based on declines in arterial stiffness, or whether reduced arterial stiffness was responsible for the fall in systolic blood pressure.
Baseline data on other complications and comorbidities such as ischemic heart disease (heart attack or bypass surgery, herein referred to as cardiovascular disease [CVD]) and hypertension (positive response to the question "Has a physician ever told you that you have had high blood pressure?") were based on self-reported physician diagnosis.
Systolic blood pressure was based on a mean of 2 readings.
Office blood pressure is based only on a single assessment, which is affected by environmental factors and does not reflect the physiological daily variability in blood pressure (23).
Our use of criteria targeting global oxygen metabolism and the mean blood pressure was based on the concept that DHP-PMX should be started before the tissues and cells have been significantly affected, even if some organ disfunction is present.
For encounters that did not have an office blood pressure documented (301 encounters), systolic and diastolic blood pressures were imputed based on the patient's office blood pressures recorded during other encounters, home blood pressure readings and all other covariates used in the construction of the multivariable model using SAS multiple imputation procedures PROC MI and PROC MIANALYZE.
Blood pressure measurements were based on the 4th Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents, published in 2004 [ 23].
Blood pressure reductions were based on the usual maintenance dose of drugs.
