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In particular, no difference was observed in weight or blood pressure changes between the etanercept and placebo groups.
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We will have similar power to detect differences in mean systolic blood pressure change between high and low literacy groups, assuming an equal distribution of literacy.
All three studies reported a significant difference in systolic blood pressure change between groups and favored pharmacist intervention (supplementary Fig. 1).
In our study, we might have seen a greater difference in systolic blood pressure change between groups if we had excluded people with normal blood pressure or well-controlled hypertension (n = 107 [41%]) or included those with elevated hypertension (≥220/120 mmHg).
Concerning more rapid injection schedules, one study [ 68] compared blood pressure changes and adverse events between 36 patients infused at a rate of 3 mg/kg/min up to a maximum dose of 15 mg/kg, 24 patients infused at 3 mg/kg/min up to 30 mg/kg, and six patients infused at 6 mg/kg/min up to 15 mg/kg.
Within-group blood pressure changes were not significant, nor were between-group blood pressure differences (Table 1).
This study sought to assess the relationship between blood pressure changes with hemodialysis and clinical outcomes during a 6-month period.
A significant relationship was found between diastolic blood pressure changes and cholesterol tertiles.
Blood pressure changes over time within groups and between groups were not significant and independent of treatment.
No significant blood pressure changes over time within groups or differences between groups were obtained (Table 2).
Simultaneous monitoring of blood pressure and intracranial pressure with comparisons of the time course of intracranial pressure and blood pressure changes could also help to tease out the relationship between systemic and brain factors.
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