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We present a 1D model including vitreous, retina, choroid and sclera subdomains with a blood phase in the retina.
Drug concentration levels in the retina have been modeled distinguishing the tissue phase from the blood phase.
This is known as extra-luminal flow (ELF) and was found to be 3-4 timoremorefficientnt in gas transfer than ILF due to the advective enhancement of the transport process in the blood phase.
While the brief liver phase of infection remains asymptomatic, the blood phase of infection causes the symptoms of the disease.
Secondly, unbound MPIO have been shown to clear rapidly from the blood stream, which minimize the background blood phase contrast [ 22].
In this study, we bridge this disconnect by measuring genome-wide translation using ribosome profiling, through five stages of the P. falciparum blood phase developmental cycle.
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In latter method, despite the volume averaging the blood of interconnect capillaries is separated from the arterial and venous blood phases.
In Figure 9 we show the sensitivity of the drug peak concentration and time-to-peak values in tissue and blood phases of the retina.
However, there was general agreement that direct contact between the gas and blood phases, which occurred in these devices, was not conducive to prolonged use surgically.
The curves relative to the retina are specified into tissue and blood phases and further divided into inner and outer region, the first indicating the portion of the retina embedding blood vessels (function (phi>1)) and the second one the avascular portion.
Figure 9 Sensitivity study of the drug peak concentration and time-to-peak values in tissue and blood phases of the retina with respect to the different components of the convective field (filtration velocity, top row and active pumping, bottom row).
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