Sentence examples for blood concentrations in vivo from inspiring English sources

These effects are seen in doses consistent with blood concentrations in vivo observed during therapy in humans [ 6].

To test the effect of blood glucose levels on VEGF concentrations in vivo, we examined plasma VEGF changes upon brief hyper- and hypoglycemia in healthy male subjects.

Leptin concentrations in vivo are high in obese patients, whereas adiponectin levels in the blood decrease with body mass index and leptin increases.

Results from the i.v. and i.p. infusion experiments confirmed that MD can be used to monitor MMC tissue concentrations in vivo, also illustrated by the reproducible relationship between concentrations calculated by intravascular MD and plasma concentrations in blood samples.

Bile-cannulated rats showed different blood concentration profiles, providing in vivo evidence for such recirculation.

Indeed, 4-CPA alone was found to be a potent inhibitor of tumour development and growth, but did not enhance RAR β expression compared to controls at 4-CPA blood concentrations that were achieved in vivo.

The remaining T cells were crippled by chronic TCR engagement, with high blood concentrations of PCV2 leading to in vivo anergy and the ultimate failure of the adaptive host immune response.

Also the experiments were done in vitro, while we measured the concentration in the blood in vivo.

In general, physiological IFN-γ probably cannot reach such high concentration in vivo.

We show here that bioconversion by mitochondria of clinically relevant concentrations of GTN results in activation of guanylate cyclase, production of cGMP, vasodilation in vitro, and lowered blood pressure in vivo, which are eliminated by genetic deletion of the mitochondrial aldehyde dehydrogenase (mtALDH).

Defining the origin of blood cells in vivo is complicated by circulation.