The readily available and easy to collect tissue in fish is blood: 97% of total fish blood comprises of RBCs.
This rudimentary analysis highlights the emergent physiology of a tissue, in this case, peripheral blood, comprising a mixture of communicating cells.
See related commentary Pulmonary artery (PA) blood comprises the mixed venous effluent from all organs, with the notable exception of the lungs.
It is noteworthy that proteins present in blood comprise the entire cohort of proteins that contribute to identification of these OA subpopulations.
Because portal venous blood comprises 75% of total hepatic blood (6 ), this condition coupled with decreased hepatic arterial blood flow as a consequence of shock might have led to severe and irreversible liver damage in this patient.
LDL, the major transporter of cholesterol within the blood, comprises a core of esterified cholesterol molecules enclosed in a shell of phospholipids and unesterified cholesterol, together with a single molecule of ApoB-100.
Based on these mutations, we propose that the CD86+ fraction in the peripheral blood comprises CLL cells that recently emigrated from lymphoid niches, where they diversified the Ig locus in an AID-dependent manner.
To robustly characterize the changes of the blood transcriptome associated with chronological age, we have build a compendium using three large-scale transcriptomic studies (Goring et al., 2007; Emilsson et al., 2008; Inouye et al., 2010) generated in blood comprising 2539 individuals on which we applied our integrative network approach.
The whole blood signature comprised genes specific of each major blood cell sub-population: granulocytes (IL8RB, NCF1 and ADAM8), monocytes (LILRA1, CCR2, CD1D), B lymphocytes (CD79A, CD180), T lymphocytes (IL7R, CD3G, CD27), platelets (CCL5, PF4 and NRGN) and reticulocytes (ALAS2, HBA2, HBA1).
