Sentence examples for blocks the maturation of from inspiring English sources
This points to the possibility that DMSO blocks the maturation of virions.
The c-Myc protein regulates the biogenesis of let-7 by stimulating Lin28 [ 46], Lin28 in turn blocks the maturation of let-7 [ 47].
Similarly, HIV-1 induces the autophagic vacuoles in macrophages during infection to enhance its replication, and its Nef protein blocks the maturation of autophagolysosomes to prevent Gag proteins from degradation [ 18, 72].
On the other hand, it blocks the maturation of autophagy to resist the degradation of autophagic contents by lysosomes, thereby leading to the accumulation of viral components and a positive regulation of apoptotic cell death.
Myc not only regulates miRNA activity during transcription, it also blocks the maturation of certain miRNAs through its cooperative relationship with some other binding proteins like Lin28, which acts as negative regulator of let-7.
The division and differentiation pattern of the stem cell-like seam cells are regulated by a well-described genetic pathway that includes several miRNAs and the LIN-28 pluripotency factor that blocks the maturation of pre- let-7 miRNA (Viswanathan and Daley, 2010).
Blocking the maturation of MVBs into lysosomes by loss of the tethering factor HPS4 (ref. 5) enhances short interfering RNA (siRNA)- and micro RNA (miRNA -mediated silencing in Drosophila miRNA -mediatedd humansilencing
Influenza A viruses of the family Orthomyxoviridae, which cause a highly contagious respiratory disease in humans, inhibit cellular macromolecular synthesis by several unique mechanisms, including blocking the maturation of cellular mRNAs and cleaving off the ends of cellular mRNAs in the nucleus of infected cells.
BFA may block the maturation of all three secretases, by trapping them in the ER, and preventing their activation in subsequent components of the secretory pathway.
In other systems, expression of α1-PDX in tumor cells blocked the maturation of MT1-MMP, leading to reduced MMP-2 activity and cell invasion [22].
Taken together, these findings show that HCV did not induce, but rather blocked, the maturation of purified pDCs and had no effect on their apoptosis.
