Sentence examples for blocks the interaction of from inspiring English sources
By interacting with Beclin-1, Bcl-2 blocks the interaction of Beclin-1 with PI3KIII, decreases PI3KIII activity, and down-regulates autophagy.
PTX3 blocks the interaction of P-selectin glycoprotein ligand-1 (PSGL-1) on neutrophils from interacting with P-selectin on the activated endothelial cells and causes neutrophil detachment rather than arrest to prevent neutrophil migration [ 32].
In conclusion, AMD3465 is a novel, monomacrocyclic anti-HIV agent that specifically blocks the interaction of HIV gp120 with CXCR4.
Namely, CCG-1423 blocks the interaction of MRTFA with importin alpha/beta 1 thus preventing the nuclear import of MRTFA [193].
Here, we define the binding site in VEGF-D of a neutralizing antibody, designated VD1, which blocks the interaction of VEGF-D with its cell surface receptors vascular endothelial growth factor receptor (VEGFR -2 and VEGFR -2and is being used for the development of therapeutic antibodies.
RIN1 interacts with BCR-ABL SH3 domain via PxxP motifs to promote autophosphorylation as well as activation of BCR-ABL tyrosine kinase, suggesting using exogenous SH3 domain which blocks the interaction of BCR-ABL and RIN1 could be an adjunct therapy for CML.
Vitaxin, a humanized monoclonal antibody that blocks the interactions of αvβ3 with its ligands, was tested as treatment for RA in clinical trials [ 101].
Assuming they utilize the same protein complex as vaccinia, he says, researchers may be able to fight these infections by blocking the interaction of the two proteins.
To better understand how various inhibitors might block the interaction of VCAM and fibronectin with α4β1, we began constructing a structure model for the integrin α4β1 complex.
We tested C-82, a therapeutic that inhibits canonical Wnt signaling by blocking the interaction of the protein CBP with β-Catenin and inhibiting Wnt-activated genes.
