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Together, our results suggest that a CD81 partner, present on Daudi and Ramos cells, blocks the interaction between CD81 and HCV glycoproteins.
Osteoblasts also synthesize and secrete OPG, a decoy receptor of RANKL, which blocks the interaction between RANKL and RANK.
Pembrolizumab (Keytruda) is a humanized monoclonal antibody that blocks the interaction between programmed death receptor-1 and its ligands.
Abatacept, a CTLA4-Ig fusion molecule, blocks the interaction between CD80/86 and CD28 and is effective in RA.
Here, we discovered that PTPN18 specifically deregulates the HER2 pY phosphorylation state and blocks the interaction between HER2 and c-Cbl, resulting in a decrease in lysosome routing.
32, 34 In contrast, SBF-1, a synthetic steroidal glycoside, blocks the interaction between PDK1 and Akt3, and, thus, could be applied to target melanoma growth and metastasis.
Similar(39)
After screening roughly 40,000 compounds, they zeroed in on one that seemed likely to work by blocking the interaction between the virus and NPC1.
Synthetic compounds mimicking such tetrapeptide motif effectively block the interaction between IAP and active caspases, thus triggering apoptosis.
Knowledge of structure and function of this system has allowed the development of inhibitors that block the interaction between the cytokines and their shared receptor.
Another potential site for intervention within the TMEN include blocking the interaction between MSCs and cancer cells by preventing MSC recruitment to tumor sites.
Accordingly, several PD-1/PD-L1 blockers have been designed to block the interaction between PD-1 and PD-L1 to enable anti-tumour immunity.
More suggestions(14)
blocks the fusion between
blocks the synapse between
blocks the friction between
blocks the distance between
blocks the junction between
blocks the engagement between
blocks the difference between
blocks the merger between
blocks the love between
blocks the doorway between
prevents the interaction between
inhibits the interaction between
impedes the interaction between
prevented the interaction between
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