Sentence examples for blocks the fusion of from inspiring English sources

Synagis (Palivizumab) blocks the fusion of RSV to its host cell membrane and is the only clinically used monoclonal antibody against an infectious disease [21].

A second class of microbicides blocks the fusion of HIV-1 with its target cells and is a large group with diverse structures; examples include cellulose sulfate, Carraguard, and PRO 2000.

Baf A1 is a lysosomal inhibitor that blocks the fusion of autophagosomes to lysosomes, thereby preventing LC3-II degradation (26).

Autophagy inhibitor chloroquine (CQ) blocks the fusion of autophagosomes and lysosomes, and results in the accumulation of LC3-II when combined with ApoG2.

To further assess the implication of autophagy in illegitimate substrate management, we measured autophagic flux in POS-exposed Sertoli cell cultures, pretreated with bafilomycin A1, which blocks the fusion of MAP1LC3A-II containing autophagosomes and lysosomes and inhibits their acidification.

Cyanovirin-N inhibits HIV-1 replication through its vivid binding to HIV-1 gp120 and as a result, inactivates the viruses and blocks the fusion of viruses to the cell membrane [ 40, 41].

To enable visualization of Lc3-II accumulation in autophagosomes, we first blocked the fusion of autophagosomes with lysosomes by treating the larvae with 2.5 μM chloroquine40 for 14 hours (h) before analysis.

Intriguingly, PLP2-TM induces incomplete autophagy process by increasing the accumulation of autophagosomes but blocking the fusion of autophagosomes with lysosomes.

These viruses likely block the fusion of autophagosomes that carry the viral replication complexes with lysosomes.

Manzamine A could block the fusion of autophagosome and lysosome and abrogate autophagosome turnover [ 13].

Bafilomycin A1 specifically inhibits AVO formation by blocking the fusion of autophagosomes and lysosomes (Yamamoto et al, 1998).